Scientists managed to increase stem cell production in the brains of aged mice using a Nobel Prize-winning gene editing technology. The research revealed that modifications in genes to prevent the slowing down of stem cells during the aging process had significant effects. Researchers from various universities in the United States utilized the Nobel Prize-winning CRISPR/Cas9 genome editing technology to boost stem cell production in the brains of mice. By making alterations to genes that slow down the production of new cells as age progresses, the scientists found that stem cell production increased in old mice. The researchers made changes in approximately 23,000 genes in mice using the CRISPR/Cas9 genome editing technology and observed that 300 different genes affecting the metabolism of mice were involved in stem cell aging. After discovering the importance of genes in cells located in the subventricular zone of both young and old mice’s brains for stem cell production, the researchers found that modifications in these genes increased the rate of stem cell production in the neurons of old mice. Furthermore, researchers found that modifying the gene called “Slc2a4” reduced the amount of glucose consumed by cells, subsequently enhancing their ability to proliferate. The study was published in the journal “Nature.”